Main artery (5)

I think it could be either:

Which length description are you looking for?:

5,4

aorta

'main artery' is the definition.
(largest artery)

This is all the clue.

(Other definitions for aorta that I've seen before include "This carries blood from the heart" , "Bloody channel" , "Main artery of body" , "A rota (anag)" , "Great artery in body" .)

I've seen this clue in The Independent, the Penny Press, the Sydney Morning Herald, The Times, The Star Tribune, the LA Times, The Mirror, the USA Today, The Sun, the King Feature Syndicate, the Evening Standard, The New York Times and The Telegraph.

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