Main subject taken by students (12)
I believe the answer is:
oceanography
'main subject' is the definition.
'oceanography' can be an answer for 'subject' (oceanography is a kind of subject). I'm unsure of the 'main' bit.
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for oceanography that I've seen before include "Scientific study of the seas" , "Study of the sea" .)