Crossword Genius

Major trading city in ancient Greece on the west coast of Asia Minor (7)

Ross

I believe the answer is:

ephesus

(Other definitions for ephesus that I've seen before include "Ancient Greek city in Turkey" , "Ancient Med. city" , "Ancient city on the coast of Asia Minor" , "Old Greek city in Turkey" , "site of ancient temple" .)

I've seen this clue in The Mirror.
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