Make a gesture or answer Italian woman (7)
I believe the answer is:
signora
'italian woman' is the definition.
(I've seen this before)
'make a gesture or answer' is the wordplay.
'make a gesture' becomes 'sign' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'answer' becomes 'a' (abbreviation eg in Q and A).
'sign'+'or'+'a'='SIGNORA'
Can you help me to learn more?
(Other definitions for signora that I've seen before include "European lady" , "lady in Milan" , "wife on the Continent" , "Italian married title" , "Young lady" .)