Make comment about spot (6)
I believe the answer is:
remark
'make comment' is the definition.
'remark' can be an answer for 'comment' (a remark is a spoken comment). I am not certain of the 'make' bit.
'about spot' is the wordplay.
'about' becomes 're' ('re' means regarding or about).
'spot' becomes 'mark' (I've seen this in other clues).
're'+'mark'='REMARK'
Can you help me to learn more?
(Other definitions for remark that I've seen before include "Notice; happen to say" , "Comment or mention" , "Observation - notice" , "(E.g. Virgil's) pastoral poems" , "Incidental observation" .)