Make for Maidenhead (4)
I believe the answer is:
form
'make' is the definition.
(synonyms)
'for maidenhead' is the wordplay.
'maidenhead' becomes 'm' (head letter of 'maiden').
'for'+'m'='FORM'
(Other definitions for form that I've seen before include "accommodation for hare" , "A hare's hide-out" , "Part of school" , "Class - questionnaire" , "Fitness" .)