Make ineffective little wave after Charlie (7)

I believe the answer is:
cripple
'make ineffective' is the definition.
The answer and definition can be both related to change as well as being verbs in their base form.
Perhaps there's an association between them I don't understand?
'little wave after charlie' is the wordplay.
'little wave' becomes 'ripple' (I've seen this in another clue).
'after' means one lot of letters go next to another.
'charlie' becomes 'C' (phonetic alphabet).
'ripple' after 'c' is 'CRIPPLE'.
Can you help me to learn more?
(Other definitions for cripple that I've seen before include "Disable - lame person" , "Incapacitate" , "Sabotage" , "Make lame" , "damage" .)
