Make random selection from actors, great numbers (4,4)
I believe the answer is:
cast lots
'make random selection' is the definition.
(to cast lots is to select something randomly)
'actors great numbers' is the wordplay.
'actors' becomes 'cast' (group of actors).
'great numbers' becomes 'lots' (large numbers of something).
'cast'+'lots'='CAST LOTS'
'from' is the link.
(Other definitions for cast lots that I've seen before include "Choose by random selection" , "Decide by random selection" , "let chance decide" .)