Make sense of the centre of the Ruhr (5)
I believe the answer is:
essen
'centre of the ruhr' is the definition.
The answer and definition can be both locations as well as being singular nouns.
Maybe there's an association between them I don't understand?
'make sense' is the wordplay.
'make' indicates an anagram.
'sense' anagrammed gives 'ESSEN'.
'of the' acts as a link.
Can you help me to learn more?
(Other definitions for essen that I've seen before include "city in the Ruhr valley" , "Industrial city of northwest Germany" , "German industrial city on the Ruhr" , "Main industrial city of the Ruhr" , "Industrial centre of the Ruhr" .)