Make sure your eyes are open (3)
I believe the answer is:
see
'make sure' is the definition.
(synonyms)
'your eyes are open' is the wordplay.
'your' becomes 'se' (I can't justify this - if you can you should give a lot more credence to this answer).
'are open' indicates taking the first letters (I've seen 'opens' mean this).
The first letter of 'eyes' is 'e'.
'se'+'e'='SEE'
Can you help me to learn more?
(Other definitions for see that I've seen before include "Observe the bishop's domain" , "Understand; watch" , "Bishop's area of control" , "Envisage; ensure" , "Perceive with eyes or mind" .)