Make up with fool? Not a chance (6,2)
I believe the answer is:
forget it
'not a chance' is the definition.
(I've seen this before)
'make up with fool?' is the wordplay.
'make up' becomes 'forge' (forging is a kind of making. I am not sure about the 'up' bit.).
'with' says to put letters next to each other.
'fool?' becomes 'tit' (I've seen this in other clues).
'forge'+'tit'='FORGET IT'
Can you help me to learn more?
(Other definitions for forget it that I've seen before include "Think no more of the matter" , "Let it go!" , "Not a chance" , "There's no need for apologies" , "ignore something" .)