Male is thrown, given an unsuitable role (7)
I believe the answer is:
miscast
'given an unsuitable role' is the definition.
(I've seen this before)
'male is thrown' is the wordplay.
'male' becomes 'm' (common abbreviation).
'thrown' becomes 'cast' (I've seen this in another clue).
'm'+'is'+'cast'='MISCAST'
(Other definitions for miscast that I've seen before include "having the wrong part" , "Given an inappropriate role" , "Given an unsuitable part" , "part poorly chosen" , "Of actor, unsuited to a role" .)