Male relative almost spoke without too much muddle (11)
I believe the answer is:
uncluttered
'without too much muddle' is the definition.
(without things being in a muddle)
'male relative almost spoke' is the wordplay.
'male relative' becomes 'uncle' (brother of a parent).
'almost' means to remove the last letter (most of the word but not all of it).
'spoke' becomes 'uttered' ('utter' can be a synonym of 'speak').
'uncle' with its final letter taken away is 'uncl'.
'uncl'+'uttered'='UNCLUTTERED'
(Other definitions for uncluttered that I've seen before include "Neat" , "Simple" , "having few things on display?" , "Spacious, tidy" .)