Malfunction of set roughly turned the wrong way (3,2)
I believe the answer is:
act up
'malfunction' is the definition.
(I've seen this before)
'set roughly turned the wrong way' is the wordplay.
'set' becomes 'put' ('put' can be a synonym of 'set').
'roughly' becomes 'ca'.
'turned the wrong way' says the letters should be written backwards.
'put'+'ca'='putca'
'putca' reversed gives 'ACT UP'.
'of' acts as a link.
(Other definitions for act up that I've seen before include "Behave badly, give trouble" , "Behave badly (colloq.)" , "Misbehave - carry on" , "Behave like a brat" , "Become unpleasant" .)