Malice spills over desire ultimately (5)
I believe the answer is:
spite
'malice' is the definition.
(synonyms)
I don't understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for spite that I've seen before include "Rancour" , "Malicious desire to hurt or humiliate" , "animosity" , "Desire to hurt or annoy" , "Desire to intentionally and maliciously hurt or offend" .)