Man approaching an area that's in South America (6)
I believe the answer is:
guyana
'in south america' is the definition.
('Guyana' is part of 'south america')
'man approaching an area' is the wordplay.
'man' becomes 'guy' (guy is a kind of man).
'approaching' says to put letters next to each other.
'area' becomes 'a' (maths abbreviation).
'guy'+'an'+'a'='GUYANA'
'that's' acts as a link.
(Other definitions for guyana that I've seen before include "Cricket-playing country" , "South American country, a British colony until 1966" , "Country E. of Venezuela" , "South American republic" , "Country of S. America" .)