Man clutching article is showing uneasiness (7)
I believe the answer is:
malaise
'uneasiness' is the definition.
(synonyms)
'man clutching article is' is the wordplay.
'man' becomes 'male' ().
'clutching' means one lot of letters goes inside another.
'article' becomes 'a' (the indefinite article in English).
'a'+'is'='ais'
'male' going around 'ais' is 'MALAISE'.
'showing' acts as a link.
(Other definitions for malaise that I've seen before include "Disquiet" , "Feeling of impending illness" , "General feeling of discomfort" , "Uneasy feeling" , "General feeling of unease or illness" .)