Man fencing in area is creating uneasiness (7)
I believe the answer is:
malaise
'uneasiness' is the definition.
(I know that uneasiness can be written as malaise)
'man fencing in area is' is the wordplay.
'man' becomes 'male'.
'fencing' means one lot of letters goes inside another (to fence can mean to contain or put a limit round).
'in area' becomes 'a' (I am not sure about this - if you are sure you should believe this answer much more).
'a'+'is'='ais'
'male' enclosing 'ais' is 'MALAISE'.
'creating' is the link.
Can you help me to learn more?
(Other definitions for malaise that I've seen before include "Feeling of impending illness" , "sickness" , "General feeling of discomfort" , "Feeling of illness or mental uneasiness" , "flu perhaps" .)