Manage to enrol recluse (5)
I believe the answer is:
loner
'recluse' is the definition.
(lonely or isolated person)
'manage to enrol' is the wordplay.
'manage' indicates an anagram (I've seen this in other clues).
'enrol' with letters rearranged gives 'LONER'.
(Other definitions for loner that I've seen before include "Isolated individual" , "Antisocial person" , "He's not a joiner" , "Recluse" , "person, one hating company" .)