Maneater makes advance prince rejected? (6)
I believe the answer is:
ogress
'maneater' is the definition.
'advance prince rejected?' is the wordplay.
'advance' becomes 'progress' ('progress' can be a synonym of 'advance').
'prince' becomes 'pr'.
'rejected?' suggests deleting specific letters.
'progress' with 'pr' taken out is 'OGRESS'.
'makes' is the link.
(Other definitions for ogress that I've seen before include "Terror" , "Frightful woman" , "Monstrous female" , "Man-eating giantess" , "Terrifying woman" .)