Crossword Genius

Manhattan area between Houston Street and Canal Street (4)

Ross

I believe the answer is:

soho

(Other definitions for soho that I've seen before include "fashionable neighbourhood (or neighborhood)" , "foreign quarter" , "District of London, noted for restaurants and nightclubs" , "(Formerly) disreputable area of London" , "London square" .)

I've seen this clue in The Times.
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