Manipulated (4)
I believe the answer is:
used
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">manipulated</span>' is the definition.<br/ ><span class="explanation-format__explanation">(using is a kind of manipulating)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for used that I've seen before include "Of clothes or cars, second-hand" , "Was treating" , "like majority of cars?" , "No longer pristine" , "Exploited group" .)