Many are loaned in extremes of poverty (6)
I believe the answer is:
plenty
'many' is the definition.
(thesaurus)
'loaned in extremes of poverty' is the wordplay.
'loaned' becomes 'lent' ('lend' can be a synonym of 'loan').
'in' is an insertion indicator.
'extremes of' means to remove the middle letters.
'poverty' with its middle removed is 'py'.
'lent' put into 'py' is 'PLENTY'.
'are' acts as a link.
(Other definitions for plenty that I've seen before include "Ample quantity" , "A full supply - lots" , "Masses" , "Amplitude or abundance" , "Many" .)