Marital problem — it leaves uneasiness (5)
I believe the answer is:
alarm
'uneasiness' is the definition.
(I've seen this before)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for alarm that I've seen before include "Strike fear" , "Frighten, scare" , "Safety bell or alert signal" , "with which many awake to in the morning" , "Device sounding danger" .)