Mark and Noel's salad with large fruits (6)
I believe the answer is:
melons
'large fruits' is the definition.
(I've seen this in another clue)
'mark and noel's salad' is the wordplay.
'mark' becomes 'm'.
'and' says to put letters next to each other.
'salad' is an anagram indicator (salad can refer to a mixture).
'noels' with letters rearranged gives 'elons'.
'm'+'elons'='MELONS'
'with' is the link.
(Other definitions for melons that I've seen before include "Lemons make other fruits" , "Juicy fruit" , "Lemons turn out to be other fruits" , "Juicy fruits" , "Fruits with hard rinds" .)