Mark somewhere in Central America (5)
I believe the answer is:
colon
I believe this clue is a double definition.
'mark' is the first definition.
(colon is a kind of mark)
'somewhere in central america' is the second definition.
(city in Panama)
(Other definitions for colon that I've seen before include "cut short dependency?" , ": - bit of the gut" , "Part of the intestine - punctuation mark" , "Part of intestines" , "cash" .)