Mark's home with writer's block (7)
I believe the answer is:
notepad
'writer's block' is the definition.
(block of paper)
'mark's home' is the wordplay.
'mark' becomes 'note' (mark can mean to note or remember).
'home' becomes 'pad' (pad can mean a person's home).
'note'+'pad'='NOTEPAD'
'with' is the link.
(Other definitions for notepad that I've seen before include "Tablet" , "Place for recording" , "type of computer" , "writer's block" , "Block of writing paper; computer" .)