Married in centre, feeling nothing (4)
I believe the answer is:
numb
'feeling nothing' is the definition.
(I've seen this before)
'married in centre' is the wordplay.
'married' becomes 'm'.
'in' means one lot of letters goes inside another.
'centre' becomes 'nub' (I've seen this before).
'm' inserted inside 'nub' is 'NUMB'.
(Other definitions for numb that I've seen before include "Unable to move" , "Unable to feel or think" , "Deprived of sensation" , "Insensate" , "Insensitive" .)