Mascot Airport confines clothing smuggler (6)
I believe the answer is:
amulet
'mascot' is the definition.
(synonyms)
'airport confines clothing smuggler' is the wordplay.
'airport confines' becomes 'at' (I can't explain this - if you can you should believe this answer much more).
'clothing' is an insertion indicator (some letters cover up or clothe others).
'smuggler' becomes 'mule' (as in a drugs mule).
'at' going around 'mule' is 'AMULET'.
Can you help me to learn more?
(Other definitions for amulet that I've seen before include "Thing worn as charm against evil" , "Jewel to protect from witchcraft" , "Charm warding off evil" , "Magical charm" , "Charm, lucky token" .)