Masterly mix-up, this motto? (5)
I believe the answer is:
maxim
'this motto?' is the definition.
(thesaurus)
'masterly mix-up' is the wordplay.
'masterly' becomes 'ma' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'up' shows that the letters should be reversed in order (in down clue: letters go upwards).
'mix' back-to-front is 'xim'.
'ma'+'xim'='MAXIM'
Can you help me to learn more?
(Other definitions for maxim that I've seen before include "Short pithy saying" , "Proverb, aphorism" , "Old machine-gun" , "Saying, adage" , "Saying - inventor of machine gun" .)