Maybe helium's left inside balloon? (5)
I believe the answer is:
glass
'balloon?' is the definition.
The answer and definition can be both man-made objects as well as being singular nouns.
Maybe they are linked in a way I don't understand?
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for glass that I've seen before include "Balloon, say" , "Vitreous material" , "Eg, tumbler" , "Perhaps schooner" , "Translucent, usually transparent, material" .)