Medic that's sore in French river mouth (10)
I believe the answer is:
embouchure
'mouth' is the definition.
(embouchure can mean a river mouth)
'medic that's sore in french river' is the wordplay.
'medic' becomes 'MB' (Bachelor of Medicine).
'that's sore' becomes 'ouch' (expression of pain).
'in' indicates putting letters inside.
'french river' becomes 'eure' (Eure is a river in France).
'mb'+'ouch'='mbouch'
'mbouch' going into 'eure' is 'EMBOUCHURE'.
(Another definition for embouchure that I've seen is " mouth".)
I've seen this clue in The Times.
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