Medical condition (8)
There are a few possibilities for this:
appendicitis
(Other definitions for disorder that I've seen before include "Chaos" , "Indiscipline" , "Do driers create untidiness?" , "[MAYHEM] ?" , "complaint" .)
(Other definitions for gangrene that I've seen before include "Mortification" , "Local death of body tissue" , "Pathological condition" , "It's mortifying" , "Localised death of body tissue" .)
(Other definitions for appendicitis that I've seen before include "Inflammation of a sac attached to the large intestine" , "Inflammation of abdominal sac" , "Inflammation for which operation may be needed" , "complaint" , "Inflammation of intestinal sac" .)