Mental sharpness of American going to university in LA, for one (6)
I believe the answer is:
acuity
'mental sharpness' is the definition.
(I've seen this before)
'american going to university in la for one' is the wordplay.
'american' becomes 'a' (common abbreviation - e.g. in organisation names).
'going to' means one lot of letters go next to another.
'university' becomes 'u' (abbreviation for university).
'in' indicates putting letters inside.
'la for one' becomes 'city' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'u' inserted into 'city' is 'cuity'.
'a'+'cuity'='ACUITY'
'of' acts as a link.
Can you help me to learn more?
(Other definitions for acuity that I've seen before include "Sharpness of mind, keenness" , "Mental sharpness" , "Showing ingenuity" , "Keenness of vision" , "Keenness of perception" .)