Mentally deranged (6)
I believe the answer is:
insane
(Other definitions for insane that I've seen before include "having a screw loose" , "Mad, irrational" , "Harebrained" , "off trolley" , "Eg, gun or knife" .)
I believe the answer is:
insane
(Other definitions for insane that I've seen before include "having a screw loose" , "Mad, irrational" , "Harebrained" , "off trolley" , "Eg, gun or knife" .)