Message from east, Irishman from south (1-4)
I believe the answer is:
'message' is the definition.
(I've seen this before)
'east irishman from south' is the wordplay.
'east' becomes 'e' (synonyms).
'irishman' becomes 'liam' (I've seen this before).
'from south' is a reversal indicator.
'liam' written backwards gives 'mail'.
'e'+'mail'='E-MAIL'
'from' acts as a link.
(Other definitions for e-mail that I've seen before include "Means of communication" , "A lime (anag.)" , "Correspondence sent via internet" , "Send a message" , "Electronic missive" .)