Message sensibly conveyed in this bottle (5)
I believe the answer is:
nerve
'this bottle' is the definition.
(I've seen this before)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for nerve that I've seen before include "Courage to carry on" , "Fearlessness" , "Impudence; courage" , "Cord that carries instructions from brain to body" , "Bundle of fibres in the body (5)" .)