Met up with scripture that's sacred (5)
I believe the answer is:
totem
'sacred' is the definition.
'met up with scripture' is the wordplay.
'up' says the letters should be written backwards (in down clue: letters go upwards).
'with' is an insertion indicator.
'scripture' becomes 'OT' (Old Testament).
'met' in reverse letter order is 'tem'.
'tem' enclosing 'ot' is 'TOTEM'.
'that's' acts as a link.
(Other definitions for totem that I've seen before include "charming symbol, say" , "emblem of tribe?" , "symbolic animal" , "Natural item of spiritual significance" , "symbol of spiritual significance" .)