Mice emptied place for grain left over in city (10)
I believe the answer is:
metropolis
'city' is the definition.
(synonyms)
'mice emptied place for grain left over' is the wordplay.
'emptied' says to hollow out the word (remove centre letters).
'place for grain' becomes 'silo' (store for grain on a farm).
'left' becomes 'port' (left side of a ship - opposite of starboard).
'over' says the letters should be written in reverse.
'mice' with its centre removed is 'me'.
'silo'+'port'='siloport'
'siloport' reversed gives 'tropolis'.
'me'+'tropolis'='METROPOLIS'
'in' is the link.
(Other definitions for metropolis that I've seen before include "Big city" , "chief centre" , "capital" , "Urban centre" , "Main city" .)