Milton Keynes for instance, is an unfamiliar place (3,4)
I believe the answer is:
new town
'milton keynes for instance' is the definition.
I can't judge whether this definition defines the answer.
'an unfamiliar place' is the wordplay.
'an unfamiliar' becomes 'new' (I've seen this in another clue).
'place' becomes 'town' (I can't explain this - if you can you should believe this answer much more).
'new'+'town'='NEW TOWN'
'is' is the link.
Can you help me to learn more?
(Other definitions for new town that I've seen before include "specially-built dwelling-place" , "Conurbation planned and built by the government" , "Planned settlement to relieve congestion" , "Basildon, perhaps ..." , "garden city?" .)