Minister and bishop aim to protect first lady (8)
I believe the answer is:
reverend
'minister' is the definition.
(I know that reverend is a type of minister)
'bishop aim to protect first lady' is the wordplay.
'bishop' becomes 'rr' (abbreviation for Right Reverend).
'aim' becomes 'end' (both can mean a goal or purpose).
'to protect' is an insertion indicator.
'first lady' becomes 'eve' (first woman in the Bible).
'rr'+'end'='rrend'
'rrend' going around 'eve' is 'REVEREND'.
'and' is the link.
(Other definitions for reverend that I've seen before include "Title of respect for a member of the clergy" , "Mother may go after this" , "Vicar's title" , "(Form of address to) clergyman" , "Title for clergyman or convent Mother" .)