Minister in bother about religious instruction (6)
I believe the answer is:
priest
'minister' is the definition.
(I've seen this before)
'bother about religious instruction' is the wordplay.
'bother' becomes 'pest'.
'about' is an insertion indicator.
'religious instruction' becomes 'RI' (abbreviation).
'pest' placed around 'ri' is 'PRIEST'.
'in' acts as a link.
(Other definitions for priest that I've seen before include "Vicar" , "Church minister" , "person of religion" , "Religious teacher" , "Art looking into" .)