Ministers, Conservative, dismissing a large adverse reaction (6)
I believe the answer is:
clergy
'ministers' is the definition.
(church ministers)
I don't understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for clergy that I've seen before include "Priesthood" , "Ordained church members" , "Ministry" , "Men of the Christian cloth" , "Religious officials" .)