Ministers left in church run to face guy on vacation (6)
I believe the answer is:
clergy
'ministers' is the definition.
(I've seen this before)
'left in church run to face guy on vacation' is the wordplay.
'left' becomes 'le' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'in' indicates putting letters inside.
'to face' suggests taking the first letters.
'on vacation' says to hollow out the word (remove centre letters).
'guy' with its middle taken out is 'gy'.
The initial letters of 'church run' is 'cr'.
'le' placed within 'cr' is 'cler'.
'cler'+'gy'='CLERGY'
Can you help me to learn more?
(Other definitions for clergy that I've seen before include "Ministry" , "Priesthood" , "Number of ministers" , "Men and women of the cloth" , "Officials of religions" .)