Minor difficulty (6)
I believe the answer is:
hiccup
'minor difficulty' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for hiccup that I've seen before include "slight setback" , "Minor setback" , "Involuntary glottal closure" , "Sudden throat sound or minor mishap" , "Temporary setback (colloq.)" .)