Miraculous place of old, sure to have changed (7)
I believe the answer is:
lourdes
'miraculous place' is the definition.
(Lourdes is associated with miracle cures)
'old sure to have changed' is the wordplay.
'to have changed' is an anagram indicator.
'old'+'sure'='oldsure'
'oldsure' with letters rearranged gives 'LOURDES'.
'of' is the link.
(Other definitions for lourdes that I've seen before include "It offers hope to the sick" , "Place of pilgrimage in the French Pyrenees" , "SW France pilgrimage site" , "Lured so to revered shrine in south of France" , "Shrine in SW France" .)