Misdirected, hikers may cry (6)
I believe the answer is:
shriek
'cry' is the definition.
(shriek is a kind of cry)
'misdirected hikers' is the wordplay.
'hikers' anagrams to 'SHRIEK'.
But, I'm not sure how this is indicated.
'may' acts as a link.
Can you help me to learn more?
(Other definitions for shriek that I've seen before include "Scream of pain or delight" , "Shrill cry of a shrike" , "Hikers (anag.)" , "Yell, screech" , "Scream or squeal" .)