Miserable individual with retired children (6)
I believe the answer is:
wretch
'miserable individual' is the definition.
'wretch' can be an answer for 'individual' (wretch is a kind of individual). I'm not certain of the 'miserable' bit.
'with retired children' is the wordplay.
'with' becomes 'w' (abbreviation).
'retired' becomes 'ret' (e.g. following the name of a retired army officer).
'children' becomes 'ch' (genealogical abbreviation).
'w'+'ret'+'ch'='WRETCH'
Can you help me to learn more?
(Other definitions for wretch that I've seen before include "Poor miserable creature" , "Unhappy person" , "Miserable fellow" , "Person in pitiful circumstances" , "Swine" .)