Miserable, lousy, cheap tit! (8)
I believe the answer is:
pathetic
'miserable' is the definition.
('pathetic' can be a synonym of 'miserable')
'lousy cheap tit' is the wordplay.
'lousy' indicates anagramming the letters.
'cheap'+'tit'='cheaptit'
'cheaptit' with letters rearranged gives 'PATHETIC'.
(Other definitions for pathetic that I've seen before include "Arousing pity or sadness" , "Wretched" , "arousing contempt" , "Sort of fallacy" , "Pitiable - paltry - touching" .)