Misery of French couple (7)
I believe the answer is:
despair
'misery' is the definition.
(I've seen this before)
'of french couple' is the wordplay.
'of french' becomes 'des' (I've seen this in other clues).
'couple' becomes 'pair' (synonyms).
'des'+'pair'='DESPAIR'
(Other definitions for despair that I've seen before include "Feeling of hopelessness" , "Despondency" , "Lose heart" , "Lose or lack hope" , "sort of counsel?" .)